About me
CV available upon request
Research
Graduate Student Researcher in Hillel Adesnik’s Lab @ UC Berkeley
May 2013 – present
- Identifying how neurons in the barrel cortex of mice represent the location of an object in its whisking field, and determining how these representations rely on multi-whisker integration and transform across the cortical layers
- Managed and optimized a two-photon microscope, and worked with the vendor on new features and fixing bugs
- Set-up and managed a large Linux server to store and secure the hundreds of TBs of data generated in the lab
- Prepared mice to express GCaMP6s, implanted chronic cranial windows, and collected neural activity data
- Developed an image analysis pipeline to identify neurons in a semi-automated fashion and pull out their activity
- Analyzed large, self-generated datasets and discovered multiple novel features of barrel cortex computation
Research Assistant in Lydia Sohn’s Lab @ UC Berkeley
May 2011 – Jun 2012
- Analyzed spatial organization of cell surface receptors in breast cancer as it correlates to different microenvironments of the cancer using Stochastic Optical Reconstruction Microscopy (STORM)
- Helped iterate and build dual channel microscope that has ability to perform TIRF, phase-contrast, and STORM
- Designed image analysis software, prepared cell cultures and buffers, and collected and analyzed STORM data
Research Assistant in Austin Roorda’s Lab @ UC Berkeley
May 2010 – Sep 2011
- Validated ability of the Adaptive Optics and Scanning Laser Ophthalmascope to identify retinal pathologies, and developed metric to objectively identify macular cone loss using spectral-domain optical coherence tomography
- Registered and processed AOSLO data, and then correlated regions of photoreceptor droupout with SDOCT
Publications
Selected Presentations
- Lyall, E. H.*, Pluta, S. R.*, Telian, G. I., Ryapolova-Webb, E., & Adesnik, H. Surround Integration Organizes a Spatial Map during Active Sensation. Scultped Light in the Brain. Berkeley, CA. 2017. Poster.
- Lyall, E. H.*, Pluta, S. R.*, Telian, G. I., Ryapolova-Webb, E., & Adesnik, H. Contextual modulation of spatial coding during active senation. Society for Neuroscience Annual Meeting. San Diego, CA. 2016. Poster.
- Pluta, S. R.*, Lyall, E. H.*, Telian, G. I., Ryapolova-Webb, E., & Adesnik, H. The role of multi-whisker integration during active sensation to the cortical representation of somatotopic space. Society for Neuroscience Annual Meeting. Chicago, IL. 2015. Poster.
- Pluta, S. R.*, Lyall, E. H.*, Telian, G. I., Ryapolova-Webb, E., & Adesnik, H. The role of multi-whisker integration during active sensation to the cortical representation of somatotopic space. Barrels XXVIII. Chicago, IL. 2015. Poster.
- Lyall, E. H., Olshausen, B. Using Sparse Coding to Identify Neural Activity in Calcium Imaging. Redwood Center for Theoretical Neuroscience Weekly Meeting. Berkeley, CA. 2013. Talk.
- Lyall, E. H., Chapman, M. R., Sohn, L. L. Characterizing Spatial Organization of Cell Surface Receptors in Human Breast Cancer with STORM. American Physical Society March Meeting. Boston, MA. 2012. Talk.
- Lyall, E. H., Roorda, A., Duncan, J. L., Schwartz, S. D., Ratnam, K., Sundquist, S., Solovyev, A. S., Lujan, B. J. Correlation Between AOSLO and SDOCT Photoreceptor Metrics in Macular Disease. Association for Research in Vision and Ophthalmology Annual Meeting. Fort Lauderdale, FL. 2011. Talk.
* Contributed equally